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Year : 2022  |  Volume : 8  |  Issue : 2  |  Page : 116-119

Repurposed oral tapentadol as an intravenous drug of abuse in opioid dependence

Department of Psychiatry, Deccan College of Medical Sciences, Hyderabad, Telangana, India

Correspondence Address:
Dr. Mazher Ali
Department of Psychiatry, Deccan College of Medical Sciences, DMRL X Road, Santosh Nagar Main Road, Kanchan Bagh, Hyderabad - 500 058, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjp.tjp_48_22

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We present to you a case series of a group of individuals who presented to us with a history of intravenous drug abuse of repurposed oral tapentadol. Tapentadol is a synthetic benzenoid with a dual mode of action, as an agonist for the μ-opioid receptor and a norepinephrine reuptake inhibitor, with potential anti-nociceptive activity. The prevalence of current opioid use in India is reported to be 4% in males and 0.2% in females. Limited availability and difficulty in procuring the recommended drugs for detoxification and maintenance therapy in opioid dependence give reasons to consider treatment alternatives for the same. This case series aims to address the need and effectiveness of evidence-based treatment in opioid dependence.

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